Benzyl-PEG3-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 1443467-88-6

Molecular Weight: 354.44

Formula: C19H30O6

Chemical Name: tert-butyl 1-phenyl-2,5,8,11-tetraoxatridecan-13-oate

Smiles: CC(C)(C)OC(=O)COCCOCCOCCOCC1C=CC=CC=1

InChiKey: CPMNHAPGRNEYDX-UHFFFAOYSA-N

InChi: InChI=1S/C19H30O6/c1-19(2,3)25-18(20)16-24-14-12-22-10-9-21-11-13-23-15-17-7-5-4-6-8-17/h4-8H,9-16H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.