Mcl-1 (phospho-Ser159/Thr163) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15006-50, ES15006-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010],

Alternate Name: Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized phosho peptide around human Mcl-1 (Ser159 and Thr163)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): About 40kd in human, 39kd in mouse and rat

Human Gene ID: 4170

Human SWISS Prot NO: Q07820

Subcellular Location: Membrane; Single-pass membrane protein. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.

Research Use Only